MyBioSource.com's Connexin 43 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, Immunohistochemistry, and Western Blot. The Connexin 43 Antibody was generated using Cnx43, Connexin 43, CX43, and GJA1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract By similarity.Toshihiko Toyofuku, J. Biol. Chem., May 1998; 273: 12725.Toshihiko Toyofuku, J. Biol. Chem., Jan 1998; 273: 1519.Masayuki Shimada, Biol Reprod, Apr 2001; 64: 1255.Merry L. Lindsey, Circulation, Jun 2006; 113: 2919 - 2928